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KMID : 0355420230470020051
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Journal of Korean Academy of Oral Health
2023 Volume.47 No. 2 p.51 ~ p.57
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Effect of a Mouthwash Containing Cetylpyridinium Chloride and zinc acetate
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Mun Ye-Rim
Choi Gil-Bok
Kim Da-Hui
Cho Ja-Won
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Abstract
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Objectives: This study investigated the effects of mouthwashes containing cetylpyridinium chlorideand zinc acetate on oral health.
Methods: A total of 60 participants were included in the study. Fifty-three participants (27 and 26participants in the experimental and control groups, respectively) were retained, excluding sevencandidates who dropped out. The mouthwash used for the study was spat out after 10-15 ml ofmouth-washing for 3 s in the oral cavity after breakfast, lunch, and dinner. Oral examination indices included the gingival (gingival index, PMA index), the patient hygiene performance (PHP index,Turesky plaque index), and the bad breath (BB checker, Oral chroma) indices. Five measurementswere taken after 2, 4, 6, 8, and 12 weeks and compared.
Results: Measurements of the gingival index showed a statistically significant difference betweenthe experimental and the control groups after 4 weeks, and the PMA index from eight weeks(P<0.05). Measurements of the PHP and Turesky plaque indices showed a significant differencein the experimental and control groups after 4 weeks (P<0.05). Compared to the PHP index beforethe experiment, that of the experimental group showed a significant index decrease after 2 weeks(P<0.05). Results of measuring bad breath through a BB checker showed a statistically significantdifference between the experimental and control groups after 4 weeks (P<0.05).
Conclusions: Oral mouthwash products containing cetylpyridinium chloride and zinc acetate relievesgingivitis, removes bacterial plaque, and reduces bad breath.
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KEYWORD
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Cetylpyridinium chloride, Mouthwash, Zinc acetate
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